Endothelin 3 anticorps (C-Term)

N° du produit ABIN926685

Cet anticorps anti-Endothelin 3 Polyclonal Lapin (ABIN926685) détecte spécifiquement Endothelin 3 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Endothelin 3 anticorps (C-Term) (ABIN926685)

Antigène: Endothelin 3 (EDN3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endothelin 3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Endothelin 3 anticorps

Épitope: C-Term

Purification: Purified

Immunogène: EDN3 antibody was raised in rabbit using the C terminal of EDN3 as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

EDN3 Blocking Peptide, (ABIN940397), is also available for use as a blocking control in assays to test for specificity of this EDN3 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Endothelin 3

Antigène: Endothelin 3 (EDN3)

Autre désignation: EDN3

Sujet: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. Synonyms: Polyclonal EDN3 antibody, Anti-EDN3 antibody, endothelin 3 antibody, ET3 antibody, MGC15067 antibody, MGC61498 antibody.

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones