RCC1 anticorps (C-Term)
Aperçu rapide pour RCC1 anticorps (C-Term) (ABIN926713)
Antigène
Voir toutes RCC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Purification
- Purified
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Immunogène
- RCC1 antibody was raised in rabbit using the C terminal of RCC1 as the immunogen
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Indications d'application
- Optimal conditions should be determined by the investigator.
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Commentaires
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RCC1 Blocking Peptide, (ABIN937009), is also available for use as a blocking control in assays to test for specificity of this RCC1 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- RCC1 (Regulator of Chromosome Condensation 1 (RCC1))
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Autre désignation
- RCC1
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Sujet
- RCC1 is a Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly. Synonyms: Polyclonal RCC1 antibody, Anti-RCC1 antibody, regulator of chromosome condensation 1 antibody, CHC1 antibody, RCC1-I antibody.
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Pathways
- Chromatin Binding, Protein targeting to Nucleus
Antigène
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