Exportin 2 anticorps (N-Term)

N° du produit ABIN926854

Cet anticorps Lapin Polyclonal détecte spécifiquement Exportin 2 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Poulet, Poisson zèbre (Danio rerio) et Xenopus laevis.

Aperçu rapide pour Exportin 2 anticorps (N-Term) (ABIN926854)

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poulet, Poisson zèbre (Danio rerio), Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Exportin 2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Exportin 2 anticorps

Épitope: N-Term

Réactivité croisée: Souris, Rat (Rattus), Poisson zebré (Brachydanio rerio), Boeuf (Vache), Grenouille, Poulet

Purification: Purified

Immunogène: CSE1 L antibody was raised in rabbit using the N terminal of CSE1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CSE1L Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CSE1L antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Exportin 2

Antigène: Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))

Autre désignation: CSE1L

Sujet: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the protein may play a role both in apoptosis and in cell proliferation. Synonyms: Polyclonal CSE1L antibody, Anti-CSE1L antibody, CSE1 chromosome segregation 1-like, yeast antibody, CAS antibody, CSE1 antibody, MGC117283 antibody, MGC130036 antibody, MGC130037 antibody, XPO2 antibody.

Pathways: Protein targeting to Nucleus