APP anticorps (C-Term)

N° du produit ABIN927396

Cet anticorps anti-APP Polyclonal Lapin (ABIN927396) détecte spécifiquement APP dans WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour APP anticorps (C-Term) (ABIN927396)

Antigène: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-APP anticorps

Épitope: C-Term

Réactivité croisée: Souris

Purification: Purified

Immunogène: App antibody was raised in rabbit using the C terminal of App as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

App Blocking Peptide, (ABIN938182), is also available for use as a blocking control in assays to test for specificity of this App antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur APP

Antigène: APP (Amyloid beta (A4) Precursor Protein (APP))

Autre désignation: App

Sujet: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a  number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of  patients with Alzheimer disease. Synonyms: Polyclonal App antibody, Anti-App antibody, amyloid beta, A4 precursor protein antibody, Ag antibody, Abpp antibody, Adap antibody, Cvap antibody, Abeta antibody, betaApp antibody, AL024401 antibody, E030013M08Rik antibody, App antibody.

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour