REST anticorps (Middle Region)

N° du produit ABIN927729

Cet anticorps anti-REST Polyclonal Lapin (ABIN927729) détecte spécifiquement REST dans WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour REST anticorps (Middle Region) (ABIN927729)

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp REST est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-REST anticorps

Épitope: Middle Region

Réactivité croisée: Souris

Purification: Purified

Immunogène: Rest antibody was raised in rabbit using the middle region of Rest as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

Rest Blocking Peptide, (ABIN936788), is also available for use as a blocking control in assays to test for specificity of this Rest antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur REST

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Autre désignation: Rest

Sujet: Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Synonyms: Polyclonal Rest antibody, Anti-Rest antibody, RE1-silencing transcription factor antibody, 2610008J04Rik antibody, AA407358 antibody, MGC150099 antibody, NRSF antibody.

Pathways: Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity