SMC1A anticorps (C-Term)

N° du produit ABIN927735

Détail du produit anti-SMC1A anticorps

Antigène: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poulet, Poisson zèbre (Danio rerio), Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMC1A est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus), Poulet, Boeuf (Vache), Chien, Grenouille, Poisson zebré (Brachydanio rerio)

Purification: Purified

Immunogène: SMC1 A antibody was raised in rabbit using the C terminal of SMC1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

SMC1A Blocking Peptide, catalog no. 33R-9611, is also available for use as a blocking control in assays to test for specificity of this SMC1A antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur SMC1A

Antigène: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Autre désignation: SMC1A (SMC1A Produits)

Synonymes: anticorps CDLS2, anticorps DXS423E, anticorps SB1.8, anticorps SMC1, anticorps SMC1L1, anticorps SMC1alpha, anticorps SMCB, anticorps SMC-1A, anticorps NV15570, anticorps 5830426I24Rik, anticorps Sb1.8, anticorps Smc1, anticorps Smc1alpha, anticorps Smc1l1, anticorps Smcb, anticorps mKIAA0178, anticorps smc1, anticorps smc1a, anticorps smc1l1, anticorps xSMC1, anticorps smc1aa, anticorps structural maintenance of chromosomes 1A, anticorps structural maintenance of chromosomes 1A b, anticorps structural maintenance of chromosomes 1A L homeolog, anticorps SMC1A, anticorps smc1a, anticorps Smc1a, anticorps smc1ab, anticorps smc1a.L

Sujet: The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by SMC1A gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the SMC1A protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. Synonyms: Polyclonal SMC1A antibody, Anti-SMC1A antibody, structural maintenance of chromosomes 1A antibody, CDLS2 antibody, DKFZp686L19178 antibody, DXS423E antibody, KIAA0178 antibody, MGC138332 antibody, SB1.8 antibody, SMC1 antibody, SMC1L1 antibody, SMC1alpha antibody, SMCB antibody.

Pathways: Stem Cell Maintenance