KEAP1 anticorps (C-Term)

N° du produit ABIN927752

L’anticorps Lapin Polyclonal anti-KEAP1 a été validé pour WB et IHC. Il convient pour détecter KEAP1 dans des échantillons de Humain, Souris, Rat, Porc, Boeuf (Vache) et Xenopus laevis.

Aperçu rapide pour KEAP1 anticorps (C-Term) (ABIN927752)

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KEAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-KEAP1 anticorps

Épitope: C-Term

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache), Porc, Grenouille

Purification: Purified

Immunogène: KEAP1 antibody was raised in rabbit using the C terminal of KEAP1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

KEAP1 Blocking Peptide, (ABIN939247), is also available for use as a blocking control in assays to test for specificity of this KEAP1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur KEAP1

Antigène: KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

Autre désignation: KEAP1

Sujet: KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests. Synonyms: Polyclonal KEAP1 antibody, Anti-KEAP1 antibody, kelch-like ECH-associated protein 1 antibody.

Pathways: Maintenance of Protein Location