HDAC3 anticorps (C-Term)

N° du produit ABIN928003

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC3 dans WB. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour HDAC3 anticorps (C-Term) (ABIN928003)

Antigène: HDAC3 (Histone Deacetylase 3 (HDAC3))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HDAC3 anticorps

Épitope: C-Term

Réactivité croisée: Rat (Rattus)

Purification: Purified

Immunogène: Hdac3 antibody was raised in rabbit using the C terminal of Hdac3 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

Hdac3 Blocking Peptide, (ABIN937608), is also available for use as a blocking control in assays to test for specificity of this Hdac3 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur HDAC3

Antigène: HDAC3 (Histone Deacetylase 3 (HDAC3))

Autre désignation: Hdac3

Sujet: Hdac3 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Hdac3 is required to repress transcription of the POU1F1 transcription factor. Hdac3 acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation. Synonyms: Polyclonal Hdac3 antibody, Anti-Hdac3 antibody, histone deacetylase 3 antibody, Hdac3 antibody.

Pathways: Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development