BMP10 anticorps (N-Term)

N° du produit ABIN928124

L’anticorps Lapin Polyclonal anti-BMP10 a été validé pour WB. Il convient pour détecter BMP10 dans des échantillons de Humain et Rat.

Aperçu rapide pour BMP10 anticorps (N-Term) (ABIN928124)

Antigène: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BMP10 anticorps

Épitope: N-Term

Réactivité croisée: Rat (Rattus)

Purification: Purified

Immunogène: Bmp10 antibody was raised in rabbit using the N terminal of Bmp10 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

Bmp10 Blocking Peptide, (ABIN939752), is also available for use as a blocking control in assays to test for specificity of this Bmp10 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur BMP10

Antigène: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Autre désignation: Bmp10

Sujet: Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth. Synonyms: Polyclonal Bmp10 antibody, Anti-Bmp10 antibody, bone morphogenetic protein 10 antibody, Bmp10 antibody.

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation