NUMA1 anticorps (C-Term)

N° du produit ABIN928379

Détail du produit anti-NUMA1 anticorps

Antigène: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NUMA1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat (Rattus), Souris, Poulet, Grenouille

Purification: Purified

Immunogène: NUMA1 antibody was raised in rabbit using the C terminal of NUMA1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

NUMA1 Blocking Peptide, catalog no. 33R-1455, is also available for use as a blocking control in assays to test for specificity of this NUMA1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur NUMA1

Antigène: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Autre désignation: NUMA1 (NUMA1 Produits)

Synonymes: anticorps NUMA, anticorps 6720401E04Rik, anticorps AA764025, anticorps AL022610, anticorps AU014979, anticorps NUMA1, anticorps NuMA, anticorps SP-H, anticorps numa, anticorps numa1, anticorps nuclear mitotic apparatus protein 1, anticorps nuclear mitotic apparatus protein 1 S homeolog, anticorps NUMA1, anticorps Numa1, anticorps numa1, anticorps numa1.S

Sujet: NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles. Synonyms: Polyclonal NUMA1 antibody, Anti-NUMA1 antibody, nuclear mitotic apparatus protein 1 antibody, NUMA antibody.

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase