PDE8A anticorps (C-Term)

N° du produit ABIN928994

Détail du produit anti-PDE8A anticorps

Antigène: PDE8A (phosphodiesterase 8A (PDE8A))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE8A est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: PDE8 A antibody was raised in rabbit using the C terminal of PDE8 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

PDE8A Blocking Peptide, catalog no. 33R-9815, is also available for use as a blocking control in assays to test for specificity of this PDE8A antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur PDE8A

Antigène: PDE8A (phosphodiesterase 8A (PDE8A))

Autre désignation: PDE8A (PDE8A Produits)

Synonymes: anticorps PDE8A, anticorps Pde8a, anticorps HsT19550, anticorps AI551852, anticorps Pde8, anticorps RNPDE8A, anticorps phosphodiesterase 8A, anticorps PDE8A, anticorps Pde8a, anticorps pde8a

Sujet: Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling. Synonyms: Polyclonal PDE8A antibody, Anti-PDE8A antibody, phosphodiesterase 8A antibody, FLJ16150 antibody, HsT19550 antibody.

Pathways: cAMP Metabolic Process