CASP5 anticorps (Middle Region)

N° du produit ABIN929108

Détail du produit anti-CASP5 anticorps

Antigène: CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CASP5 est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: CASP5 antibody was raised in rabbit using the middle region of CASP5 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CASP5 Blocking Peptide, catalog no. 33R-9599, is also available for use as a blocking control in assays to test for specificity of this CASP5 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur CASP5

Antigène: CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

Autre désignation: CASP5 (CASP5 Produits)

Synonymes: anticorps ICE(rel)III, anticorps ICEREL-III, anticorps ICH-3, anticorps CASP5, anticorps caspase 5, anticorps caspase-5, anticorps CASP5, anticorps LOC100437308

Sujet: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. Synonyms: Polyclonal CASP5 antibody, Anti-CASP5 antibody, caspase 5, apoptosis-related cysteine peptidase antibody, ICE(rel)III antibody, ICEREL-III antibody, ICH-3 antibody, MGC141966 antibody.

Pathways: Inflammasome