Caspase 10 anticorps (Middle Region)

N° du produit ABIN929111

L’anticorps anti-Caspase 10 Polyclonal Lapin est utilisé pour la détection de Caspase 10 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Caspase 10 anticorps (Middle Region) (ABIN929111)

Antigène: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Caspase 10 anticorps

Épitope: Middle Region

Purification: Purified

Immunogène: CASP10 antibody was raised in rabbit using the middle region of CASP10 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Caspase 10

Antigène: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Autre désignation: CASP10

Sujet: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. Synonyms: Polyclonal CASP10 antibody, Anti-CASP10 antibody, caspase 10, apoptosis-related cysteine peptidase antibody, ALPS2 antibody, FLICE2 antibody, MCH4 antibody.

Pathways: Apoptose, Caspase Cascade in Apoptosis