CD8 alpha anticorps (Middle Region)

N° du produit ABIN929134

Cet anticorps Lapin Polyclonal détecte spécifiquement CD8 alpha dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour CD8 alpha anticorps (Middle Region) (ABIN929134)

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD8 alpha est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CD8 alpha anticorps

Épitope: Middle Region

Purification: Purified

Immunogène: CD8 A antibody was raised in rabbit using the middle region of CD8 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CD8A Blocking Peptide, (ABIN938762), is also available for use as a blocking control in assays to test for specificity of this CD8A antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur CD8 alpha

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8A

Sujet: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal CD8A antibody, Anti-CD8A antibody, CD8a molecule antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody.

Pathways: TCR Signaling