BTBD12 anticorps (N-Term)
Aperçu rapide pour BTBD12 anticorps (N-Term) (ABIN929369)
Antigène
Voir toutes BTBD12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Purification
- Purified
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Immunogène
- BTBD12 antibody was raised in rabbit using the N terminal of BTBD12 as the immunogen
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Indications d'application
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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BTBD12 Blocking Peptide, (ABIN5612371), is also available for use as a blocking control in assays to test for specificity of this BTBD12 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))
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Autre désignation
- BTBD12
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Sujet
- This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases. Synonyms: Polyclonal BTBD12 antibody, Anti-BTBD12 antibody, BTB, POZ domain containing 12 antibody, KIAA1784 antibody, KIAA1987 antibody, MUS312 antibody, SLX4 antibody.
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Pathways
- Réparation de l'ADN
Antigène
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