Adenylosuccinate Lyase anticorps (Middle Region)
Aperçu rapide pour Adenylosuccinate Lyase anticorps (Middle Region) (ABIN929409)
Antigène
Voir toutes Adenylosuccinate Lyase (ADSL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Purification
- Purified
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Immunogène
- ADSL antibody was raised in rabbit using the middle region of ADSL as the immunogen
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Indications d'application
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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ADSL Blocking Peptide, (ABIN5611964), is also available for use as a blocking control in assays to test for specificity of this ADSL antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Adenylosuccinate Lyase (ADSL)
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Autre désignation
- ADSL
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Sujet
- Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal ADSL antibody, Anti-ADSL antibody, adenylosuccinate lyase antibody, AMPS antibody, ASASE antibody, ASL antibody.
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Pathways
- Ribonucleoside Biosynthetic Process
Antigène
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