CNTF Receptor alpha anticorps (C-Term)

N° du produit ABIN929419

Cet anticorps Lapin Polyclonal détecte spécifiquement CNTF Receptor alpha dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour CNTF Receptor alpha anticorps (C-Term) (ABIN929419)

Antigène: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTF Receptor alpha est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CNTF Receptor alpha anticorps

Épitope: C-Term

Purification: Purified

Immunogène: CNTFR antibody was raised in rabbit using the C terminal of CNTFR as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

CNTFR Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CNTFR antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur CNTF Receptor alpha

Antigène: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Autre désignation: CNTFR

Sujet: This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Synonyms: Polyclonal CNTFR antibody, Anti-CNTFR antibody, ciliary neurotrophic factor receptor antibody, MGC1774 antibody.

Pathways: Signalistation JAK/STAT, Feeding Behaviour