RHOB anticorps

N° du produit ABIN931074

Cet anticorps anti-RHOB est un anticorps Souris Monoclonal détectant RHOB dans DB. Adapté pour Humain.

Aperçu rapide pour RHOB anticorps (ABIN931074)

Antigène: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RHOB est non-conjugé

Application: Dot Blot (DB)

Clone: 2916C2a

Détail du produit anti-RHOB anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: RHOB antibody was raised in mouse using recombinant Human Ras Homolog Gene Family, Member B (Rhob)

Isotype: IgG1

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: RHOB antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur RHOB

Antigène: RHOB (Ras Homolog Gene Family, Member B (RHOB))

Autre désignation: RHOB

Sujet: RHOB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. Synonyms: Monoclonal RHOB antibody, Anti-RHOB antibody, Ras homolog gene family member B antibody, ARH6 antibody, ARHB antibody, RHOH6 antibody, MST081 antibody, MSTP081 antibody.