BPTF anticorps

N° du produit ABIN931087

Cet anticorps Souris Monoclonal détecte spécifiquement BPTF dans DB. Il présente une réactivité envers Humain.

Aperçu rapide pour BPTF anticorps (ABIN931087)

Antigène: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BPTF est non-conjugé

Application: Dot Blot (DB)

Clone: 2343C3a

Détail du produit anti-BPTF anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: FALZ antibody was raised in mouse using recombinant Human Bromodomain Phd Finger Transcription Factor (Bptf)

Isotype: IgG1

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: FALZ antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur BPTF

Antigène: BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))

Autre désignation: FALZ

Sujet: This gene was identified by the reactivity of its encoded protein to a monoclonal antibody prepared against brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), identified as an 810 aa protein containing a DNA-binding domain and a zinc finger motif, suggested it might play a role in the regulation of transcription. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. The protein encoded by this gene is actually much larger than originally thought, and it also contains a C-terminal bromodomain characteristic of proteins that regulate transcription during proliferation. Synonyms: Monoclonal FALZ antibody, Anti-FALZ antibody, Bromodomain PHD finger transcription factor antibody, BPTF antibody, FAC1 antibody, NURF301 antibody.