MXI1 anticorps

N° du produit ABIN931182

Cet anticorps anti-MXI1 est un anticorps Souris Monoclonal détectant MXI1 dans DB. Adapté pour Humain.

Aperçu rapide pour MXI1 anticorps (ABIN931182)

Antigène: MXI1 (MAX Interactor 1 (MXI1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MXI1 est non-conjugé

Application: Dot Blot (DB)

Clone: MXI1C2a

Détail du produit anti-MXI1 anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: MXI1 antibody was raised in mouse using recombinant Human Max Interactor 1

Isotype: IgG1

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: MXI1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur MXI1

Antigène: MXI1 (MAX Interactor 1 (MXI1))

Autre désignation: MXI1

Sujet: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Synonyms: Monoclonal MXI1 antibody, Anti-MXI1 antibody, MAX interacting protein 1 antibody, MAD2 antibody, MXD2 antibody, MXI antibody, MGC43220 antibody.

Pathways: Maintenance of Protein Location