NCOR1 anticorps (AA 1-192)

N° du produit ABIN931394

Détail du produit anti-NCOR1 anticorps

Antigène: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Épitope: AA 1-192

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NCOR1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Immunogène: NCOR1 antibody was raised in Mouse using a purified recombinant fragment of NCOR1(aa1-192) expressed in E. coli as the immunogen.

Clone: 7A7A9

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Détails sur NCOR1

Antigène: NCOR1 (Nuclear Receptor Co-Repressor 1 (NCOR1))

Autre désignation: NCOR1 (NCOR1 Produits)

Synonymes: anticorps ncor, anticorps zgc:56355, anticorps 5730405M06Rik, anticorps A230020K14Rik, anticorps N-CoR, anticorps RIP13, anticorps Rxrip13, anticorps mKIAA1047, anticorps N-CoR1, anticorps TRAC1, anticorps hN-CoR, anticorps nuclear receptor corepressor 1, anticorps nuclear receptor co-repressor 1, anticorps nuclear receptor corepressor 1 pseudogene, anticorps nuclear receptor corepressor 1 S homeolog, anticorps ncor1, anticorps NCOR1, anticorps CpipJ_CPIJ002507, anticorps LOC100343278, anticorps Ncor1, anticorps ncor1.S

Sujet: NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. Synonyms: Monoclonal NCOR1 antibody, Anti-NCOR1 antibody, Nuclear receptor co-repressor 1 antibody, Nuclear receptor co-repressor 1 antibody.

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process