NSD1 anticorps

N° du produit ABIN932477

L’anticorps Souris Monoclonal anti-NSD1 a été validé pour DB. Il convient pour détecter NSD1 dans des échantillons de Humain.

Aperçu rapide pour NSD1 anticorps (ABIN932477)

Antigène: NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NSD1 est non-conjugé

Application: Dot Blot (DB)

Clone: 2658C1a

Détail du produit anti-NSD1 anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: NSD1 antibody was raised in mouse using recombinant Human Nuclear Receptor Binding Set Domain Protein 1 (Nsd1)

Isotype: IgG2b

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: NSD1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur NSD1

Antigène: NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))

Autre désignation: NSD1

Sujet: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98 kDa on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. Synonyms: Monoclonal NSD1 antibody, Anti-NSD1 antibody, Nuclear receptor binding SET domain protein 1 antibody, STO antibody, KMT3B antibody, SOTOS antibody, ARA267 antibody, FLJ22263 antibody, FLJ44628 antibody, DKFZp666C163 antibody.