SMAD1 anticorps

N° du produit ABIN933125

L’anticorps Souris Monoclonal anti-SMAD1 a été validé pour WB, IP, ICC, FACS et DB. Il convient pour détecter SMAD1 dans des échantillons de Humain.

Aperçu rapide pour SMAD1 anticorps (ABIN933125)

Antigène: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SMAD1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Dot Blot (DB)

Clone: 913C1b

Détail du produit anti-SMAD1 anticorps

Réactivité croisée: Humain, Souris, Rat (Rattus)

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: SMAD1 antibody was raised in mouse using recombinant Human Smad Family Member 1 (Smad1)

Isotype: IgG1

Information d'application

Indications d'application: WB: 0.2-2 µg/mL, IP: 100-500 µg/sample, FC: 0.5-2 µg/sample, ICC: 2-100 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: SMAD1 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur SMAD1

Antigène: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Autre désignation: SMAD1

Sujet: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. Synonyms: Monoclonal SMAD1 antibody, Anti-SMAD1 antibody, Transforming growth factor beta signaling protein 1 antibody, BSP1 antibody, JV41 antibody, JV4-1 antibody, MADH1 antibody, MADR1 antibody.

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development