Resistin anticorps
Aperçu rapide pour Resistin anticorps (ABIN934075)
Antigène
Voir toutes Resistin (RETN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Immunogène
- Resistin antibody was raised in mouse using highly pure recombinant human resistin as the immunogen.
-
Isotype
- IgG2b kappa
-
-
-
-
Indications d'application
- Optimal conditions should be determined byt he investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Concentration
- Lot specific
-
Buffer
- Lyophilized from PBS.
-
Conseil sur la manipulation
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
-
-
- Resistin (RETN)
-
Autre désignation
- Resistin
-
Sujet
- Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis. Synonyms: Monoclonal Resistin antibody, Anti-Resistin antibody, FIZZ3 antibody, Adipose tissue-specific secretory factor antibody, ADSF antibody.
-
Poids moléculaire
- 20.2 kDa (predicted detection band MW)
-
Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Antigène
-