CD55 anticorps

N° du produit ABIN94183

Cet anticorps Souris Monoclonal détecte spécifiquement CD55 dans FACS, WB, IP et IHC (p). Il présente une réactivité envers Humain et Non-Human Primate et a été mentionné dans 1 publication.

Aperçu rapide pour CD55 anticorps (ABIN94183)

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD55 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MEM-118

Détail du produit anti-CD55 anticorps

Fonction: Anti-Hu CD55 Purified

Specificité: The antibody MEM-118 recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain extracellular glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.

Réactivité croisée (Details): Human, Non-Human Primates

Purification: Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).

Pureté: > 95 % (by SDS-PAGE)

Immunogène: HPB-ALL human T cell line

Isotype: IgM

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 10 μg/mL.
Immunohistochemistry (paraffin sections): Heat-mediated antigen retrieval, recommended dilution: 10 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-CD55 (ABIN94183)

Angelisová, Drbal, Horejsí, Cerný: "Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase." dans: Blood, Vol. 93, Issue 4, pp. 1437-9, (1999) (PubMed).

Détails sur CD55

Antigène: CD55 (Complement Decay-Accelerating Factor (CD55))

Autre désignation: CD55

Sujet: CD55 Molecule (Cromer blood group),CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.,DAF, CROM, CHAPLE

ID gène: 1604

UniProt: P08174

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity