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CD97 anticorps

CD97 Reactivité: Humain FACS, IP Hôte: Souris Monoclonal MEM-180 unconjugated
N° du produit ABIN94252
  • Antigène Voir toutes CD97 Anticorps
    CD97
    Reactivité
    • 66
    • 10
    • 4
    • 1
    • 1
    Humain
    Hôte
    • 53
    • 19
    • 2
    • 2
    Souris
    Clonalité
    • 57
    • 19
    Monoclonal
    Conjugué
    • 45
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD97 est non-conjugé
    Application
    • 45
    • 33
    • 28
    • 26
    • 13
    • 13
    • 10
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Specificité
    The antibody MEM-180 recognizes a unique epitope on CD97, a 75-85 kDa surface glycoprotein of G-protein-coupled receptor family, expressed on activated B and T lymphocytes, monocytes/macrophages, dendritic cells and granulocytes.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    PHA-activated peripheral blood cells
    Clone
    MEM-180
    Isotype
    IgG1
    Top Product
    Discover our top product CD97 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 5 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Wobus, Vogel, Schmücking, Hamann, Aust: "N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding." dans: International journal of cancer. Journal international du cancer, Vol. 112, Issue 5, pp. 815-22, (2004) (PubMed).

  • Antigène
    CD97
    Autre désignation
    CD97 (CD97 Produits)
    Synonymes
    anticorps AA409984, anticorps TM7LN1, anticorps adhesion G protein-coupled receptor E5, anticorps Adgre5, anticorps ADGRE5
    Sujet
    Adhesion G protein-coupled receptor E5,CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.,TM7LN1, ADGRE5
    ID gène
    976
    UniProt
    P48960
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