ALOXE3 anticorps (Middle Region)

N° du produit ABIN950356

Cet anticorps Lapin Polyclonal détecte spécifiquement ALOXE3 dans WB et EIA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ALOXE3 anticorps (Middle Region) (ABIN950356)

Antigène: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOXE3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ALOXE3 anticorps

Épitope: AA 230-260, Middle Region

Specificité: This antibody reacts to ALOXE3.

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 230-260 amino acids from the Central region of human ALOXE3

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ALOXE3

Antigène: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Autre désignation: ALOXE3

Sujet: ALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin.Synonyms: Epidermis-type lipoxygenase 3, e-LOX-3, eLOX3

ID gène: 59344

NCBI Accession: NP_001159432

Pathways: Cell-Cell Junction Organization