AMACR anticorps (C-Term)
Aperçu rapide pour AMACR anticorps (C-Term) (ABIN950388)
Antigène
Voir toutes AMACR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 330-359, C-Term
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Specificité
- This antibody reacts to AMACR.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 330-359 amino acids from the C-terminal region of human AMACR
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Autre désignation
- AMACR / RACE
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Sujet
- This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.Synonyms: 2-methylacyl-CoA racemase, Alpha-methylacyl-CoA racemase, P504S
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ID gène
- 23600
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NCBI Accession
- NP_055139
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Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
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