ARHGAP10 anticorps (Middle Region)

N° du produit ABIN950486

L’anticorps anti-ARHGAP10 Polyclonal Lapin est utilisé pour la détection de ARHGAP10 dans des échantillons de Humain. Il a été validé pour WB, IHC (p) et EIA.

Aperçu rapide pour ARHGAP10 anticorps (Middle Region) (ABIN950486)

Antigène: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP10 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-ARHGAP10 anticorps

Épitope: AA 240-267, Middle Region

Specificité: This antibody reacts to ARHGAP10.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 240-267 amino acids from the Central region of human ARHGAP10

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ARHGAP10

Antigène: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Autre désignation: ARHGAP10 / GRAF2

Sujet: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).Synonyms: GTPase regulator associated with focal adhesion kinase 2, Graf-related protein 2, Rho GTPase-activating protein 10, Rho-type GTPase-activating protein 10

ID gène: 79658

NCBI Accession: NP_078881