CD27 anticorps

N° du produit ABIN951256

Cet anticorps Hamster Monoclonal détecte spécifiquement CD27 dans FACS, IHC (p), IHC (fro) et Func. Il présente une réactivité envers Souris.

Aperçu rapide pour CD27 anticorps (ABIN951256)

Antigène: CD27 (CD27 Molecule (CD27))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD27 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: LG-3A10

Détail du produit anti-CD27 anticorps

Specificité: Recognizes Mouse CD27 receptor.

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Purification: Protein G Chromatography.

Immunogène: MCD27 tag expressing clones AR0524 and AR0530 from Armenian Hamster spleen.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD27

Antigène: CD27 (CD27 Molecule (CD27))

Autre désignation: CD27

Sujet: CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both and T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7

ID gène: 21940

NCBI Accession: NP_001028298

UniProt: P41272

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints