CD55 anticorps (PE)
Aperçu rapide pour CD55 anticorps (PE) (ABIN951352)
Antigène
Voir toutes CD55 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Specificité
- This antibody recognizes an epitope in SCR4 domain of CD55 (Decay accelerating factor, DAF), a 60-70 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein. CD55 is widely expressed on hematopoietic and on many non-hematopoietic cells, it is weakly present on NK cells.
-
Réactivité croisée (Details)
- Species reactivity (tested):Human, Non-Human Primates
-
Isotype
- IgM
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Buffer
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
-
- CD55 (Complement Decay-Accelerating Factor (CD55))
-
Autre désignation
- CD55 / DAF
-
Sujet
- CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade. Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can still regulate complement when bound to CD97. In tumours, besides protection agains complement, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis.Synonyms: Complement decay-accelerating factor
-
ID gène
- 1604
-
Pathways
- Système du Complément, Regulation of Leukocyte Mediated Immunity
Antigène
-