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Integrin beta 3 anticorps
ITGB3
Reactivité: Humain, Primate
WB, FACS, IHC (fro)
Hôte: Souris
Monoclonal
VIPL2
unconjugated
Détail du produit anti-Integrin beta 3 anticorps
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Antigène
Voir toutes Integrin beta 3 (ITGB3) Anticorps
Integrin beta 3 (ITGB3)
Reactivité
Toutes les réactivités sur Integrin beta 3 Anticorps
Humain, Primate
Hôte
Toutes les hôtes sur Integrin beta 3 Anticorps
Souris
Clonalité
Toutes les clonalités sur Integrin beta 3 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers Integrin beta 3 Anticorps
Cet anticorp Integrin beta 3 est non-conjugé
Application
Tous les applications à travers Integrin beta 3 Anticorps.
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificité
This antibody detects CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.
Réactivité croisée (Details)
Species reactivity (tested):Human, Non-Human Primates
Purification
Protein-A affinity chromatography
Pureté
> 95 % pure by SDS-PAGE
Clone
VIPL2
Isotype
IgG1
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Détails sur Integrin beta 3
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Antigène
Integrin beta 3 (ITGB3)
Autre désignation
CD61 / ITGB3 (ITGB3 Produits )
Synonymes
anticorps BDPLT16, anticorps BDPLT2, anticorps CD61, anticorps GP3A, anticorps GPIIIa, anticorps GT, anticorps INGRB3, anticorps integrin, anticorps INTB3, anticorps GPIIIA, anticorps cd61, anticorps gp3a, anticorps itgb3, anticorps itgb3.2, anticorps itgb3.1, anticorps integrin subunit beta 3, anticorps integrin beta 3, anticorps integrin subunit beta 3 L homeolog, anticorps integrin beta 3a, anticorps integrin beta 3b, anticorps ITGB3, anticorps Itgb3, anticorps itgb3.L, anticorps itgb3a, anticorps itgb3b
Sujet
CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
ID gène
3690
NCBI Accession
NP_000203
UniProt
P05106
Pathways
Regulation of G-Protein Coupled Receptor Protein Signaling , Signaling Events mediated by VEGFR1 and VEGFR2 , Smooth Muscle Cell Migration , Integrin Complex
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