Chromogranin A anticorps (C-Term)

N° du produit ABIN951517

Cet anticorps Lapin Polyclonal détecte spécifiquement Chromogranin A dans IF, FACS, WB, IHC (p) et EIA. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour Chromogranin A anticorps (C-Term) (ABIN951517)

Antigène: Chromogranin A (CHGA)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Chromogranin A est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Chromogranin A anticorps

Épitope: AA 383-412, C-Term

Specificité: This antibody reacts to CMGA.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 383-412 amino acids from the C-terminal region of human CMGA

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Chromogranin A (ABIN951517)

Shi, Duan, Liu, Zhou, Liang: "Genetic alterations and protein expression in combined small cell lung cancers and small cell lung cancers arising from lung adenocarcinomas after therapy with tyrosine kinase inhibitors." dans: Oncotarget, Vol. 7, Issue 23, pp. 34240-9, (2018) (PubMed).

Détails sur Chromogranin A

Antigène: Chromogranin A (CHGA)

Autre désignation: Chromogranin A

Sujet: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.Synonyms: CHGA, CgA, Chromogranin-A, Pituitary secretory protein I, SP-I

Poids moléculaire: 50688 Da

ID gène: 1113

NCBI Accession: NP_001266

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling