Claudin 7 anticorps (C-Term)
Aperçu rapide pour Claudin 7 anticorps (C-Term) (ABIN951552)
Antigène
Voir toutes Claudin 7 (CLDN7) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 179-209, C-Term
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Specificité
- This antibody reacts to CLDN7.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 179-209 amino acids from the C-terminal region of human CLDN7
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Claudin 7 (CLDN7)
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Autre désignation
- Claudin-7 / CLDN7
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Sujet
- This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.Synonyms: CEPTRL2, CLDN-7, CPETRL2
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Poids moléculaire
- 22418 Da
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ID gène
- 1366
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NCBI Accession
- NP_001171951
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Pathways
- Hepatitis C
Antigène
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