Coagulation Factor IX anticorps
Aperçu rapide pour Coagulation Factor IX anticorps (ABIN951595)
Antigène
Voir toutes Coagulation Factor IX (F9) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- Recognizes Human Factor IX as demonstrated by Immunodiffusion. A single positive reactivity band was observed with Normal Human Plasma. No reaction was observed against Factor IX-deficient plasma.
-
Réactivité croisée (Details)
- Species reactivity (tested):Human.
-
Purification
- Ammonium Sulfate Precipitation
-
Immunogène
- Human Factor IX purified from plasma.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 10 mg/mL
-
Buffer
- 0.01 M HEPES, pH 7.4, 0.1 M Sodium Chloride and 50 % Glycerol.
-
Agent conservateur
- Azide free
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Coagulation Factor IX (F9)
-
Sujet
- Coagulation Factor IX (F9) circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.Synonyms: Christmas factor, PTC, Plasma thromboplastin component
-
ID gène
- 2158
-
NCBI Accession
- NP_000124
Antigène
-