Anti-human factor I (C3b inactivator) monoclonal antibody clone OX-21 recognizes human complement protein factor I. Factor I has two polypeptide chains, 56 kDa and 36 kDa. This antibody detects only the 56 kDa chain. This clone has been reported not to cross react with rat.
Purification
Affinity chromatography on Protein G
Immunogène
Human complement Factor I Donor: Immunized FI cross DBA/2 x BALB/c mouse spleen cells Fusion Partner: NS-1 mouse myeloma
CFI
Reactivité: Humain
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
0,1 mg/mL
Buffer
PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
anticorps cfi, anticorps MGC53615, anticorps Cfi, anticorps factor I, anticorps IF, anticorps gb:ai721528, anticorps ahus3, anticorps c3b-ina, anticorps c3bc4bi, anticorps c3bina, anticorps kaf, anticorps CFI, anticorps AHUS3, anticorps C3BINA, anticorps C3b-INA, anticorps FI, anticorps KAF, anticorps complement factor I S homeolog, anticorps complement factor I L homeolog, anticorps complement factor I, anticorps complement component factor i, anticorps cfi.S, anticorps cfi.L, anticorps CFI, anticorps cfi, anticorps Cfi
Sujet
Factor I is a serine protease with a high degree of specificity for C3b and C4b. It requires protein cofactors for cleavage of these complement protein breakdown products: Factor H, CR1 and MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage.Synonyms: AHUS3, C3B/C4B inactivator, C3BINA, C3b-INA, CFI, IF, KAF