Complement Factor I anticorps (FITC)
Aperçu rapide pour Complement Factor I anticorps (FITC) (ABIN951648)
Antigène
Voir toutes Complement Factor I (CFI) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Anti-human factor I (C3b inactivator) monoclonal antibody clone OX-21 recognizes human complement protein factor I. Factor I has two polypeptide chains, 56 kDa and 36 kDa. This antibody detects only the 56 kDa chain. This clone has been reported not to cross react with rat.
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Purification
- Affinity chromatography on Protein G
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Immunogène
- Human complement Factor I Donor: Immunized FI cross DBA/2 x BALB/c mouse spleen cells Fusion Partner: NS-1 mouse myeloma
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0,1 mg/mL
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Buffer
- PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Complement Factor I (CFI)
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Autre désignation
- Complement Factor I
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Sujet
- Factor I is a serine protease with a high degree of specificity for C3b and C4b. It requires protein cofactors for cleavage of these complement protein breakdown products: Factor H, CR1 and MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage.Synonyms: AHUS3, C3B/C4B inactivator, C3BINA, C3b-INA, CFI, IF, KAF
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ID gène
- 3426
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NCBI Accession
- NP_000195
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UniProt
- P05156
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Pathways
- Système du Complément
Antigène
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