CRH anticorps (C-Term)

N° du produit ABIN951671

Détail du produit anti-CRH anticorps

Antigène: CRH (Corticotropin Releasing Hormone (CRH))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRH est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human Corticoliberin (C-term).

Purification: Affinity Chromatography on Protein A

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CRH

Antigène: CRH (Corticotropin Releasing Hormone (CRH))

Autre désignation: Corticoliberin (CRH Produits)

Synonymes: anticorps CRF, anticorps Gm1347, anticorps crf, anticorps crh, anticorps zgc:101864, anticorps CRH, anticorps corticoliberin, anticorps crhb, anticorps crh.1-a, anticorps crha, anticorps corticotropin releasing hormone, anticorps corticotropin releasing hormone b, anticorps corticotropin releasing hormone S homeolog, anticorps corticotropin releasing hormone L homeolog, anticorps Crh, anticorps CRH, anticorps crhb, anticorps crh, anticorps crh.S, anticorps crh.L

Sujet: Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.Synonyms: CRF, CRH, Corticotropin-Releasing Factor, Corticotropin-Releasing Hormone

Poids moléculaire: 21422 Da

ID gène: 1392

NCBI Accession: NP_000747

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Feeding Behaviour