DVL1 anticorps (Middle Region)

N° du produit ABIN951918

Cet anticorps anti-DVL1 est un anticorps Lapin Polyclonal détectant DVL1 dans WB, IF, IHC (p) et EIA. Adapté pour Humain.

Aperçu rapide pour DVL1 anticorps (Middle Region) (ABIN951918)

Antigène: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DVL1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-DVL1 anticorps

Épitope: AA 441-470, Middle Region

Specificité: This antibody recognizes Human Dishevelled-1 / DVL1 (Center).

Purification: Affinity Chromatography on Proteinn A

Immunogène: KLH conjugated synthetic peptide between 441-470 amino acids from the Central region of Human DVL1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DVL1

Antigène: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Autre désignation: Dishevelled-1 / DVL1

Sujet: DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.Synonyms: DSH homolog 1, DVL-1, Segment polarity protein dishevelled homolog DVL-1

Poids moléculaire: 75187 Da

ID gène: 1855

NCBI Accession: NP_004412

Pathways: Signalisation WNT, Synaptic Membrane, Skeletal Muscle Fiber Development