Endothelin 3 anticorps (C-Term)

N° du produit ABIN952025

L’anticorps anti-Endothelin 3 Polyclonal Lapin est utilisé pour la détection de Endothelin 3 dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour Endothelin 3 anticorps (C-Term) (ABIN952025)

Antigène: Endothelin 3 (EDN3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endothelin 3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Endothelin 3 anticorps

Épitope: AA 175-205, C-Term

Specificité: This antibody recognizes Human Endothelin-3 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogène: conjugated synthetic peptide between 175-205 amino acids from the C-terminal region of Human Endothelin-3. Genename: EDN3

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -80 °C for longer.

Détails sur Endothelin 3

Antigène: Endothelin 3 (EDN3)

Autre désignation: Endothelin-3

Sujet: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.Synonyms: EDN3, ET-3, ET3, HSCR4, MGC15067, MGC61498, PPET3, Preproendothelin-3, WS4B

Poids moléculaire: 25454 Da

ID gène: 1908

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones