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FGFRL1 anticorps (N-Term)

L’anticorps Lapin Polyclonal anti-FGFRL1 a été validé pour WB et EIA. Il convient pour détecter FGFRL1 dans des échantillons de Humain.
N° du produit ABIN952316

Aperçu rapide pour FGFRL1 anticorps (N-Term) (ABIN952316)

Antigène

Voir toutes FGFRL1 Anticorps
FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Reactivité

  • 47
  • 13
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 48
  • 2
  • 1
Lapin

Clonalité

  • 48
  • 3
Polyclonal

Conjugué

  • 21
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp FGFRL1 est non-conjugé

Application

  • 39
  • 19
  • 17
  • 13
  • 13
  • 7
  • 6
  • 6
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 15
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    This antibody reacts to FGFRL1.

    Réactivité croisée (Details)

    Species reactivity (tested):Human.

    Purification

    Affinity chromatography on Protein A

    Immunogène

    The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.

    Isotype

    Ig Fraction
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS, 0.09 % (W/V) sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

    Autre désignation

    FGFRL1

    Sujet

    Synonyms: FGF homologous factor receptor, FGFR-like protein, FGFR5, FHFR, Fibroblast growth factor receptor 5, Fibroblast growth factor receptor-like 1

    Poids moléculaire

    54537 Da

    ID gène

    53834

    NCBI Accession

    NP_001004356

    Pathways

    Signalisation RTK
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