GLIS2 anticorps (Middle Region)

N° du produit ABIN952526

Détail du produit anti-GLIS2 anticorps

Antigène: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Épitope: AA 172-202, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLIS2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human GLIS2 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 172-202 amino acids from the Central region of Human GLIS2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GLIS2

Antigène: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Autre désignation: GLIS2 (GLIS2 Produits)

Synonymes: anticorps glis2b, anticorps nkl-A, anticorps xNKLb, anticorps NKL, anticorps NPHP7, anticorps Gli5, anticorps Klf16, anticorps Nkl, anticorps glis2a, anticorps nphp7, anticorps GLIS family zinc finger 2 L homeolog, anticorps GLIS family zinc finger 2, anticorps GLIS family zinc finger 2 S homeolog, anticorps glis2.L, anticorps GLIS2, anticorps Glis2, anticorps glis2.S

Sujet: This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.Synonyms: GLI-similar 2, NKL, Neuronal Krueppel-like protein, Zinc finger protein GLIS2

Poids moléculaire: 55689 Da

ID gène: 84662

NCBI Accession: NP_115964