GLP2R anticorps (Middle Region)

N° du produit ABIN952529

L’anticorps anti-GLP2R Polyclonal Lapin est utilisé pour la détection de GLP2R dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour GLP2R anticorps (Middle Region) (ABIN952529)

Antigène: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLP2R est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-GLP2R anticorps

Épitope: AA 219-248, Middle Region

Specificité: This antibody recognizes Human GLP2R (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 219-248 amino acids from the Central region of human GLP2R

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GLP2R

Antigène: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Autre désignation: GLP2 Receptor

Sujet: The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq].Synonyms: GLP-2-R, GLP-2R, GLP2R, Glucagon-like peptide 2 receptor

Poids moléculaire: 63001 Da

ID gène: 9340

NCBI Accession: NP_004237

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Feeding Behaviour