GSTM5 anticorps (N-Term)
Aperçu rapide pour GSTM5 anticorps (N-Term) (ABIN952643)
Antigène
Voir toutes GSTM5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-51, N-Term
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Specificité
- This antibody recognizes Human GSTM5 (N-term).
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 21-51 amino acids from the N-terminal region of Human GSTM5
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GSTM5 (Glutathione S-Transferase mu 5 (GSTM5))
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Autre désignation
- GSTM5
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Sujet
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.Synonyms: GST class-mu 5, GSTM5-5, Glutathione S-transferase Mu 5
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Poids moléculaire
- 25675 Da
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ID gène
- 2949
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NCBI Accession
- NP_000842
Antigène
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