EPAS1 anticorps (N-Term)

N° du produit ABIN952733

L’anticorps Lapin Polyclonal anti-EPAS1 a été validé pour WB, FACS et EIA. Il convient pour détecter EPAS1 dans des échantillons de Humain.

Aperçu rapide pour EPAS1 anticorps (N-Term) (ABIN952733)

Antigène: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPAS1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Détail du produit anti-EPAS1 anticorps

Épitope: AA 127-154, N-Term

Specificité: This antibody recognizes Human HIF2A / HIF2 alpha (N-term).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 127-154 amino acids from the N-terminal region of Human HIF2A Genename: EPAS1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur EPAS1

Antigène: EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

Autre désignation: HIF2A / HIF2 alpha

Sujet: This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.Synonyms: BHLHE73, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, EPAS1, Endothelial PAS domain-containing protein 1, HIF-1 alpha-like factor, HIF-2 alpha, HIF-related factor, HLF, Hypoxia-inducible factor 2 alpha, MOP2, PASD2

Poids moléculaire: 96459 Da

ID gène: 2034

NCBI Accession: NP_001421

Pathways: Signaling Events mediated by VEGFR1 and VEGFR2, L'effet Warburg