KDM4B anticorps (C-Term)

N° du produit ABIN952974

Détail du produit anti-KDM4B anticorps

Antigène: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Épitope: AA 287-316, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM4B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human and Mouse JMJD2B (Thr305)

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 287~316 amino acids from the C-terminal region of human JMJD2B

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-KDM4B (ABIN952974)

Beyer, Kristensen, Jensen, Johansen, Staller: "The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF." dans: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36542-52, (2008) (PubMed).

Détails sur KDM4B

Antigène: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Autre désignation: JMJD2B / KDM4B (KDM4B Produits)

Synonymes: anticorps KDM4B, anticorps JMJD2B, anticorps jmjd2b, anticorps si:ch211-124a3.4, anticorps TDRD14B, anticorps 4732474L06Rik, anticorps Jmjd2b, anticorps mKIAA0876, anticorps lysine demethylase 4B, anticorps lysine (K)-specific demethylase 4B, anticorps KDM4B, anticorps kdm4b, anticorps Kdm4b

Sujet: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.Synonyms: JHDM3B, JmjC domain-containing histone demethylation protein 3B, Jumonji domain-containing protein 2B, KIAA0876, Lysine-specific demethylase 4B

Poids moléculaire: 121897 Da

ID gène: 23030

NCBI Accession: NP_055830

Pathways: L'effet Warburg