KDM4C anticorps (C-Term)

N° du produit ABIN952976

L’anticorps Lapin Polyclonal anti-KDM4C a été validé pour WB, FACS et EIA. Il convient pour détecter KDM4C dans des échantillons de Humain.

Aperçu rapide pour KDM4C anticorps (C-Term) (ABIN952976)

Antigène: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM4C est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Détail du produit anti-KDM4C anticorps

Épitope: AA 1030-1056, C-Term

Specificité: This antibody recognizes Human JMJD2C / KDM4C (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 1030-1056 amino acids from the C-terminal region of human JMJD2C Genename: KDM4C

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KDM4C

Antigène: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Autre désignation: JMJD2C / KDM4C

Sujet: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.Synonyms: GASC-1 protein, GASC1, Gene amplified in squamous cell carcinoma 1 protein, JHDM3C, JmjC domain-containing histone demethylation protein 3C, Jumonji domain-containing protein 2C, KIAA0780, Lysine-specific demethylase 4C

Poids moléculaire: 119982 Da

ID gène: 23081

NCBI Accession: NP_001140166

Pathways: Nuclear Hormone Receptor Binding, L'effet Warburg