KREMEN2 anticorps (Middle Region)

N° du produit ABIN953114

L’anticorps anti-KREMEN2 Polyclonal Lapin est utilisé pour la détection de KREMEN2 dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour KREMEN2 anticorps (Middle Region) (ABIN953114)

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KREMEN2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-KREMEN2 anticorps

Épitope: AA 247-276, Middle Region

Specificité: This antibody reacts to KREMEN2.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 247-276 amino acids from the Central region of human KREMEN2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KREMEN2

Antigène: KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))

Autre désignation: Kremen Protein 2

Sujet: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.Synonyms: Dickkopf receptor 2, KREMEN2, KRM2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose

ID gène: 79412

NCBI Accession: NP_078783

Pathways: Signalisation WNT