LIN7C anticorps (C-Term)

N° du produit ABIN953176

Cet anticorps Lapin Polyclonal détecte spécifiquement LIN7C dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour LIN7C anticorps (C-Term) (ABIN953176)

Antigène: LIN7C (Lin-7 Homolog C (LIN7C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN7C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-LIN7C anticorps

Épitope: AA 175-197, C-Term

Specificité: This antibody recognizes Human LIN7C (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 175-197 amino acids from the C-terminal region of Human LIN7C.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur LIN7C

Antigène: LIN7C (Lin-7 Homolog C (LIN7C))

Autre désignation: LIN7C

Sujet: LIN7C plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.Synonyms: LIN7C, Lin-7 homolog C, Lin-7C, MALS-3, MALS3, Mammalian lin-seven protein 3, VELI3, Veli-3 protein, Vertebrate lin-7 homolog 3

Poids moléculaire: 21834 Da

ID gène: 55327

NCBI Accession: NP_060832

Pathways: Synaptic Membrane