MECOM anticorps (Middle Region)

N° du produit ABIN953364

Cet anticorps anti-MECOM est un anticorps Lapin Polyclonal détectant MECOM dans WB et EIA. Adapté pour Humain et Souris.

Aperçu rapide pour MECOM anticorps (Middle Region) (ABIN953364)

Antigène: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MECOM est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-MECOM anticorps

Épitope: AA 80-109, Middle Region

Specificité: This antibody recognizes Human and Mouse MDS1 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 80-109 amino acids from the Central region of human MDS1 Genename: MECOM

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MECOM

Antigène: MECOM (MDS1 and EVI1 Complex Locus (MECOM))

Autre désignation: MDS1

Sujet: MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon (s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3,21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.Synonyms: Myelodysplasia syndrome 1, Myelodysplasia syndrome-associated protein 1

Poids moléculaire: 18696 Da

ID gène: 2122

NCBI Accession: NP_004982