MED14 anticorps (Middle Region)

N° du produit ABIN953367

Détail du produit anti-MED14 anticorps

Antigène: MED14 (Mediator Complex Subunit 14 (MED14))

Épitope: AA 585-615, Middle Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED14 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human and Mouse MED14 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 585-615 amino acids from the Central region of human MED14

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MED14

Antigène: MED14 (Mediator Complex Subunit 14 (MED14))

Autre désignation: MED14 (MED14 Produits)

Synonymes: anticorps CG12031, anticorps Dmel\\CG12031, anticorps Med14, anticorps Trap170, anticorps dTRAP170, anticorps p160, anticorps EXLM1, anticorps crsp150, anticorps crsp2, anticorps trap170, anticorps wu:fd21c05, anticorps wu:fk28h11, anticorps CRSP2, anticorps NV18605, anticorps CRSP150, anticorps CSRP, anticorps CXorf4, anticorps DRIP150, anticorps RGR1, anticorps TRAP170, anticorps 9930001L01Rik, anticorps AU041628, anticorps Crsp2, anticorps ENSMUSG00000073278, anticorps Gm641, anticorps ORF1, anticorps RGD1560170, anticorps Mediator complex subunit 14, anticorps mediator complex subunit 14, anticorps mediator of RNA polymerase II transcription subunit 14, anticorps transcriptional regulation, anticorps MED14, anticorps med14, anticorps LOC100113592, anticorps Med14, anticorps RGR1

Sujet: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.Synonyms: ARC150, Activator-recruited cofactor 150 kDa component, CRSP complex subunit 2, CRSP2, CXorf4, Cofactor required for Sp1 transcriptional activation subunit 2, DRIP150, EXLM1, Mediator of RNA polymerase II transcription subunit 14, RGR1, TRAP170 Mediator complex 14, Thyroid hormone receptor-associated protein complex 170 kDa component, Transcriptional coactivator CRSP150, Vitamin D3 receptor-interacting protein complex 150 kDa component

Poids moléculaire: 160607 Da

ID gène: 9282

NCBI Accession: NP_004220

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha